Segmentation in neuro-oncological images
Our study evaluates the impact of adding an object detection framework into brain tumour segmentation models, especially when the models are applied to different domains....
Application
Clinical
Radiomics and radiogenomics
Brain tumor is the most frequently encountered pediatric tumor. The Herby project, lead by the Institut Gustave Roussy, aims at applying radiomic, and further genomic, analysis on pediatric glioma and invasive brain stem glioma....
Imaging genetics and autism
This research involves using neuroimaging techniques genetics to study psychiatric and neurodevelopmental disorders, with a particular interest in autism spectrum disorder (ASD)....
Fundamental
The genetic architecture of language functional connectivity
Using data from the UK Biobank, the world's largest general population imaging-genetics cohort, a collaboration led by a team at BAOBAB (NeuroSpin) has identified genes involved in the genetic architecture of functional language connectivity. These genes could be a priority for studying natural language....
Heritability of the language network using resting state fMRI data
Language is a singularity of the human species. Its complexity suggests that it is supplemented by an innate language capacity....
Imaging genetics and the sulcal pits
Pits or sulcal roots are the starting marks of the sulcation process on the brain of foetus which occurs in the third semester of gestation. They have for long been assumed to be under tight genetic control, but this was never quantified. Pits are still visible in adult MR images of the brain and we studied them in the Human Connectome Project twin cohort....
Imaging genetics and sulcus opening
Gray and white matter volumes are known to reduce with age. This cortical shrinkage is visible on magnetic resonance images. Using the UK Biobank dataset, we replicated this finding and studied the genetic influence on these cortical features of aging....
The chaotic morphology of the left STS
The asymmetry of the superior temporal sulcus (STS) has been identified as a species-specific feature of the human brain. The so-called superior temporal asymmetrical pit (STAP) area is observed from the last trimester of gestation onwards and is far less pronounced in the chimpanzee brain....